<?xml version="1.0" encoding="utf-8" standalone="yes"?><rss version="2.0" xmlns:atom="http://www.w3.org/2005/Atom" xmlns:content="http://purl.org/rss/1.0/modules/content/"><channel><title>Jichen's Blog</title><link>https://antidington.github.io/</link><description>Recent content on Jichen's Blog</description><generator>Hugo</generator><language>zh-CN</language><lastBuildDate>Mon, 18 Dec 2023 23:23:15 +0800</lastBuildDate><atom:link href="https://antidington.github.io/index.xml" rel="self" type="application/rss+xml"/><item><title>Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution</title><link>https://antidington.github.io/posts/hla-single-cell-regulation/</link><pubDate>Mon, 18 Dec 2023 15:11:23 +0800</pubDate><guid>https://antidington.github.io/posts/hla-single-cell-regulation/</guid><description>&lt;h2 id="一单细胞数据集"&gt;（一）单细胞数据集&lt;/h2&gt;
&lt;ul&gt;
&lt;li&gt;69个滑膜样本&lt;/li&gt;
&lt;li&gt;22个肠样本&lt;/li&gt;
&lt;li&gt;91个PBMC体外培养样本&lt;/li&gt;
&lt;li&gt;OneK1K cohort&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;img loading="lazy" src="https://antidington.github.io/posts/hla-single-cell-regulation/images/17027072677260.jpg"&gt;&lt;/p&gt;
&lt;h2 id="二pseudobulk-cell-type-specific-eqtl"&gt;（二）Pseudobulk cell type specific eQTL&lt;/h2&gt;
&lt;ul&gt;
&lt;li&gt;由于作者关注HLA基因，所以只对相关的髓系细胞、T细胞、B细胞进行了分析&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;img loading="lazy" src="https://antidington.github.io/posts/hla-single-cell-regulation/images/17027078386181.jpg"&gt;&lt;/p&gt;</description></item></channel></rss>